Nicotine EP Impurity A

Nicotine EP Impurity A - Names and Identifiers

Name	3-[(2S)-1,2,3,6-tetrahydropyridin-2-yl]pyridine
Synonyms	ANABATINE S-(-)-ANATABINE Nicotine EP Impurity A Nicotine EP Impurity A (Anatabine) (S)-1,2,3,6-tetrahydro-2,3'-bipyridine [2S,(-)]-1,2,3,6-Tetrahydro-2,3'-bipyridine (2S)-2-(3-Pyridyl)-1,2,3,6-tetrahydropyridine 3-[(2S)-1,2,3,6-tetrahydropyridin-2-yl]pyridine
CAS	581-49-7

Nicotine EP Impurity A - Physico-chemical Properties

Molecular Formula	C10H12N2
Molar Mass	160.22
Density	1.0910
Boling Point	276.13°C (rough estimate)
pKa	8.84±0.40(Predicted)
Storage Condition	-20°C Freezer, Under Inert Atmosphere
Refractive Index	1.5676

Nicotine EP Impurity A - Introduction

(S)-(-) anatabine (3-[(2S)-1,2,3,6-tetrahydropyridin-2-yl]pyridine) is a chiral compound, its chemical name is (S)-(-)-3-(1,2,3,6-tetrahydropyridin-2-yl) pyridine. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless solid
-Solubility: Soluble in water and organic solvents such as ethanol and methanol
-Melting point: About 122-125 ℃
-Molecular weight: 160.23g/mol

Use:
(S)-(-) anotabine has certain uses in the field of pharmacy and biochemistry, such:
-As a drug intermediate: It can be used as an intermediate for the synthesis of some drugs in the field of medicine.
-Biochemical Research: Neotabine has some applications in the study of neurotransmitters, receptor structure and antibacterial activity.

Method:
(S)-(-) Neotacinoid is generally obtained by chemical synthesis. There are a variety of synthetic routes available, one of the common methods is to use a synthetic reaction with a chiral determination step to obtain a chiral product.

Safety Information:
When handling (S)-(-) Neotacinine, the following safety precautions need to be paid attention:
-Avoid direct skin contact, inhalation and ingestion.
-Wear appropriate protective gloves, goggles and a protective mask when operating.
-Follow proper laboratory safety procedures and store and dispose of this compound properly.

Last Update：2024-04-09 19:05:57